Eplerenone in Patients with Systolic Heart Failure and Mild Symptoms

Zannad, Faı̈ez; J.V. McMurray, John; Krum, Henry; J. van Veldhuisen, Dirk; Swedberg, Karl; Shi, Harry; Vincent, John; Pocock, Stuart; Pitt, Bertram

doi:10.1056/nejmoa1009492

Public

Eplerenone in Patients with Systolic Heart Failure and Mild Symptoms

Published in New England Journal of Medicine • Nov 14, 2010

Authors:

Faı̈ez Zannad

John J.V. McMurray

Henry Krum

Abstract

BACKGROUND: Mineralocorticoid antagonists improve survival among patients with chronic, severe systolic heart failure and heart failure after myocardial infarction. We evaluated the effects of eplerenone in patients with chronic systolic heart failure and mild symptoms. METHODS: In this randomized, ...

Subject

Eplerenone

Medicine

Heart failure

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