New loci associated with kidney function and chronic kidney disease

Köttgen, Anna; Pattaro, Cristian; A. Böger, Carsten; Fuchsberger, Christian; Olden, Matthias; L. Glazer, Nicole; Parsa, Afshin; Gao, Xiaoyi; Yang, Qiong; V. Smith, Albert; R. O’Connell, Jeffrey; Li, Man; Schmidt, Helena; Tanaka, Toshiko; Isaacs, Aaron; Ketkar, Shamika; Hwang, Shih-Jen; D. Johnson, Andrew; Dehghan, Abbas; Teumer, Alexander; Paré, Guillaume; J. Atkinson, Elizabeth; Zeller, Tanja; Lohman, Kurt; C. Cornelis, Marilyn; Probst‐Hensch, Nicole; Kronenberg, Florian; Tönjes, Anke; Hayward, Caroline; Aspelund, Thor; Eiríksdóttir, Guðný; J. Launer, Lenore; B. Harris, Tamara; Rampersaud, Evadnie; D. Mitchell, Braxton; E. Arking, Dan; Boerwinkle, Eric; Struchalin, Maksim; Cavalieri, Margherita; B. Singleton, Andrew; Giallauria, Francesco; Metter, Jeffrey; H. de Boer, Ian; Haritunians, Talin; Lumley, Thomas; S. Siscovick, David; M. Psaty, Bruce; Carola Zillikens, M; A. Oostra, Ben; F. Feitosa, Mary; A. Province, Michael; de Andrade, Mariza; T. Turner, Stephen; Schillert, Arne; Ziegler, Andreas; S. Wild, Philipp; B. Schnabel, Renate; Wilde, Sandra; F. Münzel, Thomas; S. Leak, Tennille; Illig, Thomas; Klopp, Norman; Meisinger, Christa; Wichmann, H‐Erich; Köenig, Wolfgang; Zgaga, Lina; Zemunik, Tatijana; Kolčić, Ivana; Minelli, Cosetta; B. Hu, Frank; Johansson, Åsa; Igl, Wilmar; Zaboli, Ghazal; H. Wild, Sarah; F. Wright, Alan; Campbell, Harry; Ellinghaus, David; Schreiber, Stefan; S. Aulchenko, Yurii; F. Felix, Janine; Rivadeneira, Fernando; G. Uitterlinden, André; Hofman, Albert; Imboden, Medea; Nitsch, Dorothea; Kloss‐Brandstätter, Anita; Kollerits, Barbara; Kedenko, Lyudmyla; Mägi, Reedik; Stümvoll, Michael; Kovács, Péter; Boban, Mladen; Campbell, Susan; Endlich, Karlhans; Völzke, Henry; K. Kroemer, Heyo; Nauck, Matthias; Völker, Uwe; Polašek, Ozren; Vitart, Véronique; Badola, Sunita; N. Parker, Alexander; M. Ridker, Paul; L. R. Kardia, Sharon; Blankenberg, Stefan; Liu, Ching‐Ti; C. Curhan, Gary; Franke, André; Rochat, Thierry; Paulweber, Bernhard; Prokopenko, Inga; Wang, Wei; Guðnason, Vilmundur; R. Shuldiner, Alan; Coresh, Josef; Schmidt, Reinhold; Ferrucci, Luigi; G. Shlipak, Michael; M. van Duijn, Cornelia; B. Borecki, Ingrid; K. Krämer, Bernhard; Rudan, Igor; Gyllensten, Ulf; F. Wilson, James; C.M. Witteman, Jacqueline; P. Pramstaller, Peter; Rettig, Rainer; Hastie, Nick; I. Chasman, Daniel; Linda Kao, W.H.; M. Heid, Iris; S. Fox, Caroline

doi:10.1038/ng.568

Public

New loci associated with kidney function and chronic kidney disease

Published in Nature Genetics • Apr 11, 2010

Authors:

Anna Köttgen

Cristian Pattaro

Carsten A. Böger

Abstract

Caroline Fox and colleagues report results of a large genome-wide association meta-analysis and replication study for indices of renal function. Their work identifies 13 new loci associated with renal function and 7 loci associated with creatinine production and secretion. Chronic kidney disease (CK...

Subject

Biology

Kidney disease

Renal function

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