COLD ISCHEMIA TIME: AN INDEPENDENT PREDICTOR OF INCREASED HLA CLASS I ANTIBODY PRODUCTION AFTER REJECTION OF A PRIMARY CADAVERIC RENAL ALLOGRAFT1

Bryan, Christopher; M. Luger, Alan; Martinez, John; Muruve, Nic; W. Nelson, Paul; E. Pierce, George; Ross, Gilbert; F. Shield, Charles; A. Warady, Bradley; I. Aeder, Mark; S. Helling, Thomas

doi:10.1097/00007890-200104150-00009

Public

COLD ISCHEMIA TIME: AN INDEPENDENT PREDICTOR OF INCREASED HLA CLASS I ANTIBODY PRODUCTION AFTER REJECTION OF A PRIMARY CADAVERIC RENAL ALLOGRAFT1

Published in Transplantation • Apr 1, 2001

Authors:

Christopher Bryan

Alan M. Luger

John Martinez

Abstract

BACKGROUND: Cadaveric kidneys experiencing longer cold ischemia time (CIT) are associated with higher levels of delayed graft function, acute rejection, and early graft loss. One mechanism to explain these results is that ischemia/reperfusion (I/R) injury makes the allograft more immunogenic by upre...

Subject

Panel reactive antibody

Medicine

Cadaveric spasm

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