Genomewide Association Study of an AIDS‐Nonprogression Cohort Emphasizes the Role Played by<i>HLA</i>Genes (ANRS Genomewide Association Study 02)

Limou, Sophie; Le Clerc, Sigrid; Coulonges, Cédric; Carpentier, Wassila; Dina, Christian; Delaneau, Olivier; Labib, Taoufik; Taing, Lieng; Sladek, Robert; Genomic Group, ANRS; Deveau, Christiane; Ratsimandresy, Rojo; Montès, Matthieu; Spadoni, Jean‐Louis; Lelièvre, Jean‐Daniel; Lévy, Yves; Therwath, Amu; Schächter, François; Matsuda, Fumihiko; Gut, Marta; Froguel, Philippe; Delfraissy, Jean‐François; Herçberg, Serge; Zagury, Jean‐François

doi:10.1086/596067

Public

Genomewide Association Study of an AIDS‐Nonprogression Cohort Emphasizes the Role Played byHLAGenes (ANRS Genomewide Association Study 02)

Published in The Journal of Infectious Diseases • Dec 30, 2008

Authors:

Sophie Limou

Sigrid Le Clerc

Cédric Coulonges

Abstract

To elucidate the genetic factors predisposing to AIDS progression, we analyzed a unique cohort of 275 human immunodeficiency virus (HIV) type 1-seropositive nonprogressor patients in relation to a control group of 1352 seronegative individuals in a genomewide association study (GWAS). The strongest ...

Subject

Genome-wide association study

Single-nucleotide polymorphism

Linkage disequilibrium

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