Comparative Immunogenicity and Efficacy of 13-Valent and 7-Valent Pneumococcal Conjugate Vaccines in Reducing Nasopharyngeal Colonization: A Randomized Double-Blind Trial

Dagan, Ron; D. Patterson, Scott; Juergens, Christine; Greenberg, David; Givon‐Lavi, Noga; Porat, Nurith; Gurtman, Alejandra; C. Gruber, William; A. Scott, Daniel

doi:10.1093/cid/cit428

Public

Comparative Immunogenicity and Efficacy of 13-Valent and 7-Valent Pneumococcal Conjugate Vaccines in Reducing Nasopharyngeal Colonization: A Randomized Double-Blind Trial

Published in Clinical Infectious Diseases • Jun 26, 2013

Authors:

Ron Dagan

Scott D. Patterson

Christine Juergens

Abstract

BACKGROUND: The 13-valent pneumococcal conjugate vaccine (PCV13) was licensed to replace the 7-valent pneumococcal conjugate vaccine (PCV7) based on serological noninferiority criteria. To date no randomized PCV13 pediatric trial has included clinical endpoints. METHODS: This randomized double-blind...

Subject

Pneumococcal conjugate vaccine

Serotype

Medicine

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