Proposal for Standardization of Optimized Mycobacterial Interspersed Repetitive Unit-Variable-Number Tandem Repeat Typing of Mycobacterium tuberculosis

Supply, Philip; Allix, Caroline; Lesjean, Sarah; Cardoso-Oelemann, Mara; Rüsch–Gerdes, Sabine; Willery, Eve; Savin, Evgeny; de Haas, Petra; van Deutekom, Henk; Roring, Solvig; Bifani, Pablo; Kurepina, Natalia; N. Kreiswirth, Barry; Sola, Christophe; Rastogi, Nalin; Vatin, Vincent; Cristina Gutierrez, Maria; Fauville, Maryse; Niemann, Stefan; Skuce, Robin; Kremer, Kristin; Locht, Camille; van Soolingen, Dick

doi:10.1128/jcm.01392-06

Public

Proposal for Standardization of Optimized Mycobacterial Interspersed Repetitive Unit-Variable-Number Tandem Repeat Typing of Mycobacterium tuberculosis

Published in Journal of Clinical Microbiology • Dec 1, 2006

Authors:

Philip Supply

Caroline Allix

Sarah Lesjean

Abstract

Molecular typing based on 12 loci containing variable numbers of tandem repeats of mycobacterial interspersed repetitive units (MIRU-VNTRs) has been adopted in combination with spoligotyping as the basis for large-scale, high-throughput genotyping of Mycobacterium tuberculosis. However, even the com...

Subject

Variable number tandem repeat

Genotyping

Biology

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