<i>Mycobacterium tuberculosis</i>
                    Modulates Macrophage Lipid-Sensing Nuclear Receptors PPARγ and TR4 for Survival

Mahajan, Sahil; Kitdorlang Dkhar, H; Chandra, Vemika; Dave, Sandeep; Nanduri, Ravikanth; Kumar Janmeja, Ashok; N Agrewala, Javed; Gupta, Pawan

doi:10.4049/jimmunol.1103038

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Mycobacterium tuberculosis Modulates Macrophage Lipid-Sensing Nuclear Receptors PPARγ and TR4 for Survival

Shared by NobleBlocks on Jun 1, 2012 • 12:00 AM UTC

Authors:

Sahil Mahajan

H Kitdorlang Dkhar

Vemika Chandra

Abstract

Abstract Mycobacterium tuberculosis–macrophage interactions are key to pathogenesis and clearance of these bacteria. Although interactions between M. tuberculosis-associated lipids and TLRs, non-TLRs, and opsonic receptors have been investigated, interactions of these lipids and infected macrophage ...

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