The Transient Receptor Potential Protein Homologue TRP6 Is the Essential Component of Vascular α1-Adrenoceptor–Activated Ca2+-Permeable Cation Channel

Inoue, Ryuji; Okada, Takaharu; Onoue, Hitoshi; Hara, Yuji; Shimizu, Shunichi; Naitoh, Shinji; Ito, Yushi; Mori, Yasuo

doi:10.1161/01.res.88.3.325

Public

The Transient Receptor Potential Protein Homologue TRP6 Is the Essential Component of Vascular α1-Adrenoceptor–Activated Ca2+-Permeable Cation Channel

Published in Circulation Research • Feb 16, 2001

Authors:

Ryuji Inoue

Takaharu Okada

Hitoshi Onoue

Abstract

The Drosophila transient receptor potential protein (TRP) and its mammalian homologues are thought to be Ca(2+)-permeable cation channels activated by G protein (G(q/11))-coupled receptors and are regarded as an interesting molecular model for the Ca(2+) entry mechanisms associated with stimulated p...

Subject

Transient receptor potential channel

Receptor

Component (thermodynamics)

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