Oral Apixaban for the Treatment of Acute Venous Thromboembolism

Agnelli, Giancarlo; R. Büller, Harry; T. Cohen, Alexander; Curto, Madelyn; Gallus, Alexander; Johnson, Margot; Masiukiewicz, Urszula; Pak, Raphael; R. Thompson, John; E. Raskob, Gary; I. Weitz, Jeffrey

doi:10.1056/nejmoa1302507

Public

Oral Apixaban for the Treatment of Acute Venous Thromboembolism

Published in New England Journal of Medicine • Jul 1, 2013

Authors:

Giancarlo Agnelli

Harry R. Büller

Alexander T. Cohen

Abstract

BACKGROUND: Apixaban, an oral factor Xa inhibitor administered in fixed doses, may simplify the treatment of venous thromboembolism. METHODS: In this randomized, double-blind study, we compared apixaban (at a dose of 10 mg twice daily for 7 days, followed by 5 mg twice daily for 6 months) with conve...

Subject

Apixaban

Medicine

Venous thromboembolism

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