Effectiveness of Adjunctive Antidepressant Treatment for Bipolar Depression

S. Sachs, Gary; A. Nierenberg, Andrew; R. Calabrese, Joseph; B. Marangell, Lauren; R. Wisniewski, Stephen; Gyulai, L.; S. Friedman, Edward; L. Bowden, Charles; D. Fossey, Mark; J. Ostacher, Michael; A. Ketter, Terence; K. Patel, Jayendra; Hauser, Péter; Rapport, Daniel; M. Martinez, James; H. Allen, Michael; J. Miklowitz, David; W. Otto, Michael; B. Dennehy, Ellen; E. Thase, Michael

doi:10.1056/nejmoa064135

Public

Effectiveness of Adjunctive Antidepressant Treatment for Bipolar Depression

Published in New England Journal of Medicine • Mar 28, 2007

Authors:

Gary S. Sachs

Andrew A. Nierenberg

Joseph R. Calabrese

Abstract

BACKGROUND: Episodes of depression are the most frequent cause of disability among patients with bipolar disorder. The effectiveness and safety of standard antidepressant agents for depressive episodes associated with bipolar disorder (bipolar depression) have not been well studied. Our study was de...

Subject

Antidepressant

Depression (economics)

Bipolar disorder

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