Five Versus More Than Five Years of Tamoxifen Therapy for Breast Cancer Patients With Negative Lymph Nodes and Estrogen Receptor-Positive Tumors

Fisher, Bernard; J. Dignam, James; Bryant, John; P. DeCillis, Arthur; Lawrence Wickerham, D.; Wolmark, Norman; P. Costantino, Joseph; Redmond, Carol; R. Fisher, Edwin; M. J. S. Bowman, David; Deschênes, L; V Dimitrov, N; G. Margolese, Richard; Robidoux, A.; R. Shibata, Henry; J. Terz, Jose; Paterson, Alexander; I. Feldman, Merrill; Farrar, William; F. Evans, James; Lavina A. Lickley, H.

doi:10.1093/jnci/88.21.1529

Public

Five Versus More Than Five Years of Tamoxifen Therapy for Breast Cancer Patients With Negative Lymph Nodes and Estrogen Receptor-Positive Tumors

Published in JNCI Journal of the National Cancer Institute • Nov 6, 1996

Authors:

Bernard Fisher

James J. Dignam

John Bryant

Abstract

BACKGROUND: In 1982, the National Surgical Adjuvant Breast and Bowel Project initiated a randomized, double-blinded, placebo-controlled trial (B-14) to determine the effectiveness of adjuvant tamoxifen therapy in patients with primary operable breast cancer who had estrogen receptor-positive tumors ...

Subject

Tamoxifen

Medicine

Breast cancer

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