Highly Efficient Capture of Circulating Tumor Cells by Using Nanostructured Silicon Substrates with Integrated Chaotic Micromixers

Wang, Shutao; Liu, Kan; Liu, Jian; Tak For Yu, Zeta; Xu, Xiaowen; Zhao, Libo; Lee, Tom; Kyung Lee, Eun; Reiss, Jean; Lee, Yi‐Kuen; W.K. Chung, Leland; Huang, Jiaoti; B. Rettig, Matthew; B. Seligson, David; N. Duraiswamy, Kumaran; Kwang-Fu Shen, Clifton; Tseng, Hsian‐Rong

doi:10.1002/anie.201005853

Public

Highly Efficient Capture of Circulating Tumor Cells by Using Nanostructured Silicon Substrates with Integrated Chaotic Micromixers

Published in Angewandte Chemie International Edition • Mar 4, 2011

Authors:

Shutao Wang

Kan Liu

Jian Liu

Abstract

Finding a needle in a haystack: A new technology is demonstrated to enrich circulating tumor cells (CTCs) with high efficiency by integrating an antibody-coated silicon nanopillar (SiNP, see picture; gray) substrate with an overlaid polydimethylsiloxane (PDMS) microfluidic chaotic mixer (turquoise)....

Subject

Haystack

Circulating tumor cell

Computer science

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