Analysis of surgical margins with the molecular marker eIF4E: a prognostic factor in patients with head and neck cancer.

CO, Nathan; S, Franklin; FW, Abreo; R, Nassar; Benedetti A, De; J, Glass

doi:10.1200/jco.1999.17.9.2909

Public

Analysis of surgical margins with the molecular marker eIF4E: a prognostic factor in patients with head and neck cancer.

Shared by NobleBlocks on Sep 1, 1999 • 12:00 AM UTC

Authors:

Nathan CO

Franklin S

Abreo FW

Abstract

Purpose Complete excision of cancer is guided by histologic assessment of surgical margins. Molecular markers may be more sensitive in identifying malignant cells. eIF4E, a eukaryotic protein synthesis initiation factor, is found elevated in all head and neck squamous cell cancers (HNSCC). In a prel...

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