A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β

J. Iliff, Jeffrey; Wang, Minghuan; Liao, Yonghong; A. Plogg, Benjamin; Peng, Weiguo; A. Gundersen, Georg; Benveniste, Helene; Edward Vates, G.; Deane, Rashid; A. Goldman, Steven; A. Nagelhus, Erlend; Nedergaard, Maiken

doi:10.1126/scitranslmed.3003748

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A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β

Shared by NobleBlocks on Aug 15, 2012 • 12:00 AM UTC

Authors:

Jeffrey J. Iliff

Minghuan Wang

Yonghong Liao

Abstract

Cerebrospinal fluid flows through channels around brain blood vessels that are bounded by astrocytic endfeet, mediated by water transport through aquaporin-4.

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