Epithelial‐mesenchymal transition spectrum quantification and its efficacy in deciphering survival and drug responses of cancer patients

Zea Tan, Tuan; Hao Miow, Qing; Miki, Yoshio; Noda, Tetsuo; Mori, Seiichi; Yun‐Ju Huang, Ruby; Paul Thiery, Jean

doi:10.15252/emmm.201404208

Public

Epithelial‐mesenchymal transition spectrum quantification and its efficacy in deciphering survival and drug responses of cancer patients

Published in EMBO Molecular Medicine • Sep 11, 2014

Authors:

Tuan Zea Tan

Qing Hao Miow

Yoshio Miki

Abstract

Epithelial-mesenchymal transition (EMT) is a reversible and dynamic process hypothesized to be co-opted by carcinoma during invasion and metastasis. Yet, there is still no quantitative measure to assess the interplay between EMT and cancer progression. Here, we derived a method for universal EMT sco...

Subject

Epithelial–mesenchymal transition

Colorectal cancer

Ovarian cancer

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