The <i>Polycomb</i>-Group Gene<i>Ezh2</i> Is Required for Early Mouse Development

O’Carroll, Dónal; Erhardt, Sylvia; Pagani, Michaela; C. Barton, Sheila; Azim Surani, M.; Jenuwein, Thomas

doi:10.1128/mcb.21.13.4330-4336.2001

Public

The Polycomb-Group GeneEzh2 Is Required for Early Mouse Development

Published in Molecular and Cellular Biology • Jul 1, 2001

Authors:

Dónal O’Carroll

Sylvia Erhardt

Michaela Pagani

Abstract

Polycomb-group (Pc-G) genes are required for the stable repression of the homeotic selector genes and other developmentally regulated genes, presumably through the modulation of chromatin domains. Among the Drosophila Pc-G genes, Enhancer of zeste [E(z)] merits special consideration since it represe...

Subject

Biology

EZH2

Homeotic gene

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!