The Shikimate Pathway and Its Branches in Apicomplexan Parasites

W. Roberts, Craig; Roberts, Fiona; E. Lyons, Russell; J. Kirisits, Michael; Mui, Ernest; R. Finnerty, John; J. Johnson, Jennifer; Ferguson, David; R. Coggins, John; Krell, Tino; H. Coombs, Graham; K. Milhous, Wilbur; E. Kyle, Dennis; Tzipori, Saul; W. Barnwell, John; B. Dame, John; M. Carlton, Jane; McLeod, Rima

doi:10.1086/338004

Public

The Shikimate Pathway and Its Branches in Apicomplexan Parasites

Published in The Journal of Infectious Diseases • Feb 15, 2002

Authors:

Craig W. Roberts

Fiona Roberts

Russell E. Lyons

Abstract

The shikimate pathway is essential for production of a plethora of aromatic compounds in plants, bacteria, and fungi. Seven enzymes of the shikimate pathway catalyze sequential conversion of erythrose 4-phosphate and phosphoenol pyruvate to chorismate. Chorismate is then used as a substrate for othe...

Subject

Shikimate pathway

Aromatic amino acids

Biochemistry

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