Dizocilpine but not ketamine reduces the volume of ischaemic damage after acute subdural haematoma in the rat

Uchida, Kentaro; Nakakimura, Kazuhiko; Kuroda, Yuichi; Haranishi, Yasunori; Matsumoto, Mishiya; Sakabe, T

doi:10.1046/j.0265-0215.2000.00825.x

Public

Dizocilpine but not ketamine reduces the volume of ischaemic damage after acute subdural haematoma in the rat

Published in European Journal of Anaesthesiology • May 1, 2001

Authors:

Kentaro Uchida

Kazuhiko Nakakimura

Yuichi Kuroda

Abstract

BACKGROUND AND OBJECTIVE: Increased glutamate concentration in the cerebrospinal fluid has been reported in severely head-injured patients, suggesting that an excessive release of glutamate may be involved in the process of neuronal damage. Ischaemic damage after subdural haematoma has been reported...

Subject

Dizocilpine

Medicine

Anesthesia

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