OnabotulinumtoxinA for treatment of chronic migraine: pooled results from the double-blind, randomized, placebo-controlled phases of the PREEMPT clinical program.

W Dodick, David; C Turkel, Catherine; E DeGryse, Ronald; K Aurora, Sheena; D Silberstein, Stephen; B Lipton, Richard; Diener, Hans-Christoph; F Brin, Mitchell; Chronic Migraine Study Group, PREEMPT

doi:10.1111/j.1526-4610.2010.01678.x

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OnabotulinumtoxinA for treatment of chronic migraine: pooled results from the double-blind, randomized, placebo-controlled phases of the PREEMPT clinical program.

Shared by NobleBlocks on Jun 1, 2010 • 12:00 AM UTC

Authors:

David W Dodick

Catherine C Turkel

Ronald E DeGryse

Abstract

OBJECTIVE: To assess the efficacy, safety, and tolerability of onabotulinumtoxinA (BOTOX) as headache prophylaxis in adults with chronic migraine. BACKGROUND: Chronic migraine is a prevalent, disabling, and undertreated neurological disorder. Few preventive treatments have been investigated and none...

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