Peroxisome Proliferator-Activated Receptor γ Plays a Critical Role in Inhibition of Cardiac Hypertrophy In Vitro and In Vivo

Asakawa, Masayuki; Takano, Hiroyuki; Nagai, Toshio; Uozumi, Hiroki; Hasegawa, Hiroshi; Kubota, Naoto; Saito, Toshihiro; Masuda, Yoshiaki; Kadowaki, Takashi; Komuro, Issei

doi:10.1161/hc1002.105225

Public

Peroxisome Proliferator-Activated Receptor γ Plays a Critical Role in Inhibition of Cardiac Hypertrophy In Vitro and In Vivo

Published in Circulation • Mar 12, 2002

Authors:

Masayuki Asakawa

Hiroyuki Takano

Toshio Nagai

Abstract

BACKGROUND: Peroxisome proliferator-activated receptors (PPARs) are transcription factors of the nuclear receptor superfamily. It has been reported that the thiazolidinediones, which are antidiabetic agents and high-affinity ligands for PPARgamma, regulate growth of vascular cells. In the present st...

Subject

Pioglitazone

Internal medicine

Endocrinology

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!