Prehospital Use of Magnesium Sulfate as Neuroprotection in Acute Stroke

L. Saver, Jeffrey; Starkman, Sidney; Eckstein, Marc; J. Stratton, Samuel; D Pratt, Franklin; Hamilton, Scott; Conwit, Robin; S. Liebeskind, David; Sung, Gene; Kramer, Ian; Moreau, G.; T. Goldweber, Robert; Sanossian, Nerses

doi:10.1056/nejmoa1408827

Public

Prehospital Use of Magnesium Sulfate as Neuroprotection in Acute Stroke

Published in New England Journal of Medicine • Feb 4, 2015

Authors:

Jeffrey L. Saver

Sidney Starkman

Marc Eckstein

Abstract

BACKGROUND: Magnesium sulfate is neuroprotective in preclinical models of stroke and has shown signals of potential efficacy with an acceptable safety profile when delivered early after stroke onset in humans. Delayed initiation of neuroprotective agents has hindered earlier phase 3 trials of neurop...

Subject

Medicine

Interquartile range

Stroke (engine)

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