The mouse homolog of Drosophila Vasa is required for the development of male germ cells

Restricted expression of a mouse Vasa homolog gene ( Mvh ) expression is first detected in primordial germ cells (PGCs) after colonization of the genital ridges. Subsequently, Mvh is maintained until postmeiotic germ cells are formed. Here, we demonstrate that male mice homozygous for a targeted mut... View More