Defining Breast Cancer Intrinsic Subtypes by Quantitative Receptor Expression

C.U. Cheang, Maggie; Martín, Miguel; O. Nielsen, Torsten; Prat, Aleix; Voduc, David; Rodríguez-Lescure, Álvaro; Ruı́z, Amparo; Chia, Stephen; E. Shepherd, Lois; Ruíz‐Borrego, Manuel; Calvo, Lourdes; Alba, Emilio; Carrasco, Eva; Caballero, Rosalía; Tu, Dongsheng; I. Pritchard, Kathleen; N. Levine, Mark; Bramwell, Vivien; S. Parker, Joel; S. Bernard, Philip; J. Ellis, Matthew; M. Perou, Charles; Di Leo, Angelo; A. Carey, Lisa

doi:10.1634/theoncologist.2014-0372

Public

Defining Breast Cancer Intrinsic Subtypes by Quantitative Receptor Expression

Published in The Oncologist • Apr 23, 2015

Authors:

Maggie C.U. Cheang

Miguel Martín

Torsten O. Nielsen

Abstract

PURPOSE: To determine intrinsic breast cancer subtypes represented within categories defined by quantitative hormone receptor (HR) and HER2 expression. METHODS: We merged 1,557 cases from three randomized phase III trials into a single data set. These breast tumors were centrally reviewed in each tr...

Subject

Breast cancer

Expression (computer science)

Cancer

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