Irinotecan plus oxaliplatin and leucovorin-modulated fluorouracil in advanced pancreatic cancer--a Groupe Tumeurs Digestives of the Federation Nationale des Centres de Lutte Contre le Cancer study.

T, Conroy; B, Paillot; E, François; R, Bugat; JH, Jacob; U, Stein; S, Nasca; JP, Metges; O, Rixe; P, Michel; E, Magherini; A, Hua; G, Deplanque

doi:10.1200/jco.2005.06.050

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Irinotecan plus oxaliplatin and leucovorin-modulated fluorouracil in advanced pancreatic cancer--a Groupe Tumeurs Digestives of the Federation Nationale des Centres de Lutte Contre le Cancer study.

Shared by NobleBlocks on Feb 1, 2005 • 12:00 AM UTC

Authors:

Conroy T

Paillot B

François E

Abstract

Purpose To evaluate response rate and toxicity of irinotecan and oxaliplatin plus fluorouracil (FU) and leucovorin (Folfirinox) in advanced pancreatic adenocarcinoma (APA).Patients and methods Chemotherapy-naive patients with histologically proven APA and bidimensionally measurable disease were trea...

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