Tumor Burden Influences Cytotoxic T Cell Development in Metastatic Breast Cancer Patients—A Phase I/II Study

E. Wright, Stephen; Rewers‐Felkins, Kathleen; S. Quinlin, Imelda; Phillips, Catherine; K. Townsend, Mary; Philip, Ramila; Zorsky, Paul; Klug, Panpit; Dai, Lijun; Hussain, Mohammad; A. Thomas, Aabu; Sundaramurthy, Chithraleka

doi:10.3109/08820130903278089

Public

Tumor Burden Influences Cytotoxic T Cell Development in Metastatic Breast Cancer Patients—A Phase I/II Study

Published in Immunological Investigations • Oct 28, 2009

Authors:

Stephen E. Wright

Kathleen Rewers‐Felkins

Imelda S. Quinlin

Abstract

The influence of tumor burden on the generation of tumor antigen-specific cytotoxic T-lymphocytes (CTL) was investigated in a phase I/II clinical adoptive immunotherapy trial. Four previously treated metastatic breast cancer patients, two with macroscopic disease and two with no evidence of disease,...

Subject

CTL*

Medicine

Cytotoxic T cell

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