Phase 1b randomized trial and follow-up study in Uganda of the blood-stage malaria vaccine candidate BK-SE36.

NM, Palacpac; E, Ntege; A, Yeka; B, Balikagala; N, Suzuki; H, Shirai; M, Yagi; K, Ito; W, Fukushima; Y, Hirota; C, Nsereko; T, Okada; BN, Kanoi; K, Tetsutani; N, Arisue; S, Itagaki; T, Tougan; KJ, Ishii; S, Ueda; TG, Egwang; T, Horii

doi:10.1371/journal.pone.0064073

Public

Phase 1b randomized trial and follow-up study in Uganda of the blood-stage malaria vaccine candidate BK-SE36.

Shared by NobleBlocks on May 28, 2013 • 12:00 AM UTC

Authors:

Palacpac NM

Ntege E

Yeka A

Abstract

Background Up to now a malaria vaccine remains elusive. The Plasmodium falciparum serine repeat antigen-5 formulated with aluminum hydroxyl gel (BK-SE36) is a blood-stage malaria vaccine candidate that has undergone phase 1a trial in malaria-naive Japanese adults. We have now assessed the safety and...

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