Human Ccr4-Not complexes contain variable deadenylase subunits.

NC, Lau; A, Kolkman; Schaik FM, van; KW, Mulder; WW, Pijnappel; AJ, Heck; HT, Timmers

doi:10.1042/bj20090500

Public

Human Ccr4-Not complexes contain variable deadenylase subunits.

Shared by NobleBlocks on Aug 27, 2009 • 12:00 AM UTC

Authors:

Lau NC

Kolkman A

van Schaik FM

Abstract

The Ccr4-Not complex is evolutionarily conserved and important for regulation of mRNA synthesis and decay. The composition of the yeast complex has been well described. Orthologues of the yeast Ccr4-Not components have been identified in human cells including multiple subunits with mRNA deadenylase ...

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