The Organization, Promoter Analysis, and Expression of the Human PPARγ Gene

Fajas, Lluís; Auboeuf, Didier; Raspé, Eric; Schoonjans, Kristina; Lefebvre, Anne‐Marie; Saladin, Régis; Najib, Jamilla; Laville, Martine; Fruchart, Jean‐Charles; S. Deeb, Samir; Vidal‐Puig, Antonio; S. Flier, Jeffrey; R. Briggs, Michael; Staels, Bart; Vidal, Hubert; Auwerx, Johan

doi:10.1074/jbc.272.30.18779

Public

The Organization, Promoter Analysis, and Expression of the Human PPARγ Gene

Published in Journal of Biological Chemistry • Jul 1, 1997

Authors:

Lluís Fajas

Didier Auboeuf

Eric Raspé

Abstract

PPARgamma is a member of the PPAR subfamily of nuclear receptors. In this work, the structure of the human PPARgamma cDNA and gene was determined, and its promoters and tissue-specific expression were functionally characterized. Similar to the mouse, two PPAR isoforms, PPARgamma1 and PPARgamma2, wer...

Subject

Peroxisome proliferator-activated receptor

Biology

Exon

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