Florbetaben PET imaging to detect amyloid beta plaques in Alzheimer's disease: Phase 3 study

Sabri, Osama; N. Sabbagh, Marwan; Seibyl, John; Barthel, Henryk; Akatsu, Hiroyasu; Ouchi, Yasuomi; Senda, Kohei; Murayama, Shigeo; Ishii, Kenji; Takao, Masaki; G. Beach, Thomas; C. Rowe, Christopher; B. Leverenz, James; Ghetti, Bernardino; W. Ironside, James; M. Catafau, Ana; Stephens, Andrew; Mueller, André; Koglin, Norman; Hoffmann, Anja; Roth, Katrin; Reininger, Cornelia; Schulz‐Schaeffer, Walter; Phase 3 Study Group, Florbetaben

doi:10.1016/j.jalz.2015.02.004

Public

Florbetaben PET imaging to detect amyloid beta plaques in Alzheimer's disease: Phase 3 study

Published in Alzheimer s & Dementia • Mar 27, 2015

Authors:

Osama Sabri

Marwan N. Sabbagh

John Seibyl

Abstract

BACKGROUND: Evaluation of brain β-amyloid by positron emission tomography (PET) imaging can assist in the diagnosis of Alzheimer disease (AD) and other dementias. METHODS: Open-label, nonrandomized, multicenter, phase 3 study to validate the (18)F-labeled β-amyloid tracer florbetaben by comparing in...

Subject

Histopathology

Senile plaques

Medicine

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