Evolution of pathogenicity and sexual reproduction in eight Candida genomes

Butler, Geraldine; D. Rasmussen, Matthew; Lin, Michael; A. S. Santos, Manuel; Sakthikumar, Sharadha; A. Munro, Carol; Rheinbay, Esther; Grabherr, Manfred; Forche, Anja; L. Reedy, Jennifer; Agrafioti, Ino; B. Arnaud, Martha; Bates, Steven; J. P. Brown, Alistair; Brunke, Sascha; C. Costanzo, Maria; A. Fitzpatrick, David; W. J. de Groot, Piet; Harris, David; L. Hoyer, Lois; Hube, Bernhard; M. Klis, Frans; D. Kodira, Chinnappa; Lennard, Nicola; E. Logue, Mary; Martin, Ronny; M. Neiman, Aaron; Nikolaou, Elissavet; A. Quail, Michael; Quinn, Janet; C. Santos, Maria; Schmitzberger, Florian; Sherlock, Gavin; Shah, Prachi; A.T. Silverstein, Kevin; S. Skrzypek, Marek; R. Soll, David; Staggs, Rodney; Stansfield, Ian; P. H. Stumpf, Michael; E. Sudbery, Peter; Srikantha, Thyagarajan; Zeng, Qiandong; Berman, Judith; Berriman, Matthew; Heitman, Joseph; A. R. Gow, Neil; Lorenz, Michael; W. Birren, Bruce; Kellis, Manolis; A. Cuomo, Christina

doi:10.1038/nature08064

Public

Evolution of pathogenicity and sexual reproduction in eight Candida genomes

Published in Nature • May 24, 2009

Authors:

Geraldine Butler

Matthew D. Rasmussen

Michael Lin

Abstract

Candida species are the most common cause of opportunistic fungal infection worldwide. Here we report the genome sequences of six Candida species and compare these and related pathogens and non-pathogens. There are significant expansions of cell wall, secreted and transporter gene families in pathog...

Subject

Biology

Genetics

Mating type

Research Assistant

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