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Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function.

Published in Proceedings of the National Academy of Sciences of the United States of America • Sep 25, 2007
Authors:
John W Elrod
,
John W Calvert
,
Joanna Morrison

Abstract

The recent discovery that hydrogen sulfide (H(2)S) is an endogenously produced gaseous second messenger capable of modulating many physiological processes, much like nitric oxide, prompted us to investigate the potential of H(2)S as a cardioprotective agent. In the current study, we demonstrate that...

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