Toll‐like receptor 4 ligand can differentially modulate the release of cytokines by human platelets

Cognasse, Fabrice; Hamzeh‐Cognasse, Hind; Lafarge, Sandrine; Delezay, Olivier; Pozzetto, Bruno; McNicol, Archie; Garraud, Olivier

doi:10.1111/j.1365-2141.2008.06999.x

Public

Toll‐like receptor 4 ligand can differentially modulate the release of cytokines by human platelets

Shared by NobleBlocks on Feb 13, 2008 • 12:00 AM UTC

Authors:

Fabrice Cognasse

Hind Hamzeh‐Cognasse

Sandrine Lafarge

Abstract

Summary Blood platelets link the processes of haemostasis and inflammation. This study examined the immunomodulatory factors released by platelets after Toll‐Like Receptor 4 (TLR4) engagement on their surfaces. Monoclonal anti‐human FcγRII Ab (IV.3)‐treated human platelets were cultured with TLR4 li...

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