Toll‐like receptor 4 ligand can differentially modulate the release of cytokines by human platelets

Cognasse, Fabrice; Hamzeh‐Cognasse, Hind; Lafarge, Sandrine; Delézay, Olivier; Pozzetto, Bruno; McNicol, Archie; Garraud, Olivier

doi:10.1111/j.1365-2141.2008.06999.x

Public

Toll‐like receptor 4 ligand can differentially modulate the release of cytokines by human platelets

Published in British Journal of Haematology • Feb 13, 2008

Authors:

Fabrice Cognasse

Hind Hamzeh‐Cognasse

Sandrine Lafarge

Abstract

Blood platelets link the processes of haemostasis and inflammation. This study examined the immunomodulatory factors released by platelets after Toll-Like Receptor 4 (TLR4) engagement on their surfaces. Monoclonal anti-human FcgammaRII Ab (IV.3)-treated human platelets were cultured with TLR4 ligand...

Subject

Platelet

Angiogenin

TLR4

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