Hereditary diffuse gastric cancer: updated consensus guidelines for clinical management and directions for future research

C. Fitzgerald, Rebecca; Hardwick, Richard; G. Huntsman, David; Carneiro, Fátima; Guilford, Parry; Blair, Vanessa; C. Chung, Daniel; A. Norton, Jeffrey; Ragunath, Krish; Han van Krieken, J.; Dwerryhouse, S; Caldas, Carlos

doi:10.1136/jmg.2009.074237

Public

Hereditary diffuse gastric cancer: updated consensus guidelines for clinical management and directions for future research

Published in Journal of Medical Genetics • Jun 30, 2010

Authors:

Rebecca C. Fitzgerald

Richard Hardwick

David G. Huntsman

Abstract

25-30% of families fulfilling the criteria for hereditary diffuse gastric cancer have germline mutations of the CDH1 (E-cadherin) gene. In light of new data and advancement of technologies, a multidisciplinary workshop was convened to discuss genetic testing, surgery, endoscopy and pathology reporti...

Subject

Medicine

Breast cancer

Cancer

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