Effects of Hypothermia and Hyperthermia on Cytokine Production by Cultured Human Mononuclear Phagocytes from Adults and Newborns

D. Fairchild, Karen; M. Viscardi, Rose; Hester, Lisa; Singh, Ishwar; D. Hasday, Jeffrey

doi:10.1089/107999000750053708

Public

Effects of Hypothermia and Hyperthermia on Cytokine Production by Cultured Human Mononuclear Phagocytes from Adults and Newborns

Published in Journal of Interferon & Cytokine Research • Dec 1, 2000

Authors:

Karen D. Fairchild

Rose M. Viscardi

Lisa Hester

Abstract

We have shown previously that febrile range temperatures modify cytokine production by adult macrophages. In this study, we compared the effects of moderate hyperthermia and hypothermia on the kinetics of lipopolysaccharide (LPS)-induced cytokine expression in monocytes and macrophages of newborns a...

Subject

Cytokine

Hyperthermia

Lipopolysaccharide

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