The frequency of EGFR and KRAS mutations in non-small cell lung cancer (NSCLC): routine screening data for central Europe from a cohort study

Boch, Christian; Kollmeier, Jens; Röth, Andreas; Stephan-Falkenau, Susann; Misch, Daniel; Grüning, W; Bauer, Torsten; Mairinger, Thomas

doi:10.1136/bmjopen-2013-002560

Public

The frequency of EGFR and KRAS mutations in non-small cell lung cancer (NSCLC): routine screening data for central Europe from a cohort study

Published in BMJ Open • Jan 1, 2013

Authors:

Christian Boch

Jens Kollmeier

Andreas Röth

Abstract

OBJECTIVES: Owing to novel therapy strategies in epidermal growth factor receptor (EGFR)-mutated patients, molecular analysis of the EGFR and KRAS genome has become crucial for routine diagnostics. Till date these data have been derived mostly from clinical trials, and thus collected in pre-selected...

Subject

Medicine

KRAS

Lung cancer

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