Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Integrity Is Required for Insulin Signaling and Is Implicated in Hepatic Insulin Resistance

Tubbs, Emily; Theurey, Pierre; Vial, Guillaume; Bendridi, Nadia; Bravard, Amélie; Chauvin, Marie‐Agnès; Cao, J.; Zoulim, Fabien; Bartosch, Birke; Ovize, Michel; Vidal, Hubert; Rieusset, Jennifer

doi:10.2337/db13-1751

Public

Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Integrity Is Required for Insulin Signaling and Is Implicated in Hepatic Insulin Resistance

Published in Diabetes • Jun 20, 2014

Authors:

Emily Tubbs

Pierre Theurey

Guillaume Vial

Abstract

Mitochondria-associated endoplasmic reticulum (ER) membranes (MAMs) are functional domains between both organelles involved in Ca(2+) exchange, through the voltage-dependent anion channel (VDAC)-1/glucose-regulated protein 75 (Grp75)/inositol 1,4,5-triphosphate receptor (IP3R)-1 complex, and regulat...

Subject

VDAC1

Endoplasmic reticulum

Insulin resistance

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!