Imaging considerations for in vivo <sup>13</sup>C metabolic mapping using hyperpolarized <sup>13</sup>C‐pyruvate

Yen, Yi‐Fen; J. Kohler, Susan; Chen, A.P.; A. Tropp, Joel; Bok, Robert; Wolber, Jan; J. Albers, Mark; Gram, K.A.; L. Zierhut, Matthew; Park, I.; Zhang, V.; Hu, Simon; Nelson, S.J.; B. Vigneron, Daniel; Kurhanewicz, John; Dirven, Hubert; E. Hurd, Ralph

doi:10.1002/mrm.21987

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Imaging considerations for in vivo 13C metabolic mapping using hyperpolarized 13C‐pyruvate

Published in Magnetic Resonance in Medicine • Mar 24, 2009

Authors:

Yi‐Fen Yen

Susan J. Kohler

A.P. Chen

Abstract

One of the challenges of optimizing signal-to-noise ratio (SNR) and image quality in (13)C metabolic imaging using hyperpolarized (13)C-pyruvate is associated with the different MR signal time-courses for pyruvate and its metabolic products, lactate and alanine. The impact of the acquisition time wi...

Subject

Image quality

Nuclear magnetic resonance

Signal-to-noise ratio (imaging)

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