Early Impairment of Gut Function and Gut Flora Supporting a Role for Alteration of Gastrointestinal Mucosa in Human Immunodeficiency Virus Pathogenesis

Gori, Andrea; Tincati, Camilla; Rizzardini, Giuliano; Torti, Carlo; Quirino, Tiziana; Haarman, Monique; Ben Amor, Kaouther; van Schaik, Jacqueline; J. M. Vriesema, Aldwin; Knol, Jan; Marchetti, Giulia; W. Welling, Gjalt; Clerici, Mario

doi:10.1128/jcm.01729-07

Public

Early Impairment of Gut Function and Gut Flora Supporting a Role for Alteration of Gastrointestinal Mucosa in Human Immunodeficiency Virus Pathogenesis

Published in Journal of Clinical Microbiology • Dec 19, 2007

Authors:

Andrea Gori

Camilla Tincati

Giuliano Rizzardini

Abstract

Our results show that impairment of the gastrointestinal tracts in human immunodeficiency virus (HIV)-positive patients is present in the early phases of HIV disease. This impairment is associated with alterations in gut microbiota and intestinal inflammatory parameters. These findings support the h...

Subject

Pathogenesis

Gastrointestinal tract

Biology

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