Gold nanorods with a hematoporphyrin-loaded silica shell for dual-modality photodynamic and photothermal treatment of tumors in vivo

S. Terentyuk, Georgy; Panfilova, Elizaveta; A. Khanadeev, Vitaly; С. Чумаков, Д.; A. Genina, Elina; N. Bashkatov, Alexey; V. Tuchin, Valery; B. Bucharskaya, Alla; N. Maslyakova, Galina; G. Khlebtsov, Nikolai; N. Khlebtsov, Boris

doi:10.1007/s12274-013-0398-3

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Gold nanorods with a hematoporphyrin-loaded silica shell for dual-modality photodynamic and photothermal treatment of tumors in vivo

Published in Nano Research • Jan 3, 2014

Authors:

Georgy S. Terentyuk

Elizaveta Panfilova

Vitaly A. Khanadeev

Abstract

Nanocomposites (NCs) consisting of a gold nanorod core and a mesoporous silica shell doped with hematoporphyrin (HP) have been fabricated in order to improve the efficiency of cancer treatment by combining photothermal and photodynamic therapies (PDT + PTT) in vivo. In addition to the long-wavelengt...

Subject

Photothermal therapy

Hematoporphyrin

Nanorod

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