Reduction of Nightmares and Other PTSD Symptoms in Combat Veterans by Prazosin: A Placebo-Controlled Study

A. Raskind, Murray; R. Peskind, Elaine; D. Kanter, Evan; C. Petrie, Eric; D. Radant, Allen; E. Thompson, Charles; J. Dobie, Dorcas; J. Hoff, David; J. Rein, Rebekah; Straits-Tröster, Kristy; G. Thomas, Ronald; M. McFall, Miles

doi:10.1176/appi.ajp.160.2.371

Public

Reduction of Nightmares and Other PTSD Symptoms in Combat Veterans by Prazosin: A Placebo-Controlled Study

Published in American Journal of Psychiatry • Jan 31, 2003

Authors:

Murray A. Raskind

Elaine R. Peskind

Evan D. Kanter

Abstract

OBJECTIVE: Prazosin is a centrally active alpha(1) adrenergic antagonist. The authors' goal was to evaluate prazosin efficacy for nightmares, sleep disturbance, and overall posttraumatic stress disorder (PTSD) in combat veterans. METHOD: Ten Vietnam combat veterans with chronic PTSD and severe traum...

Subject

Prazosin

Placebo

Psychology

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