Validating novel tau positron emission tomography tracer
                    <scp>[F‐18]‐AV‐1451 (T807)</scp>
                    on postmortem brain tissue

Marquié, Marta; D. Normandin, Marc; R. Vanderburg, Charles; M. Costantino, Isabel; A. Bien, Elizabeth; G. Rycyna, Lisa; E. Klunk, William; A. Mathis, Chester; D. Ikonomovic, Milos; L. Debnath, Manik; Vasdev, Neil; C. Dickerson, Bradford; N. Gomperts, Stephen; H. Growdon, John; A. Johnson, Keith; P. Frosch, Matthew; T. Hyman, Bradley; Gómez‐Isla, Teresa

doi:10.1002/ana.24517

Public

Validating novel tau positron emission tomography tracer [F‐18]‐AV‐1451 (T807) on postmortem brain tissue

Shared by NobleBlocks on Sep 25, 2015 • 12:00 AM UTC

Authors:

Marta Marquié

Marc D. Normandin

Charles R. Vanderburg

Abstract

Objective To examine region‐ and substrate‐specific autoradiographic and in vitro binding patterns of positron emission tomography tracer [F‐18]‐AV‐1451 (previously known as T807), tailored to allow in vivo detection of paired helical filament‐tau–containing lesions, and to determine whether there i...

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