Level of <i>HER2</i> Gene Amplification Predicts Response and Overall Survival in HER2-Positive Advanced Gastric Cancer Treated With Trastuzumab

Gomez-Martin, Carlos; Carlos Plaza, Jose; Pazo-Cid, Roberto; Salud, Antonieta; Pons, Francesc; Fonseca, Paula; Leon, Ana; Alsina, Maria; Visa, Laura; Rivera, Fernando; Carmen Galan, M.; del Valle, Elena; Vilardell, Felipe; Iglesias, Mar; Fernandez, Soledad; Landolfi, Stefania; Cuatrecasas, Miriam; Mayorga, Marta; Jose Paulés, M.; Sanz-Moncasi, Pilar; Montagut, Clara; Garralda, Elena; Rojo, Federico; Hidalgo, Manuel; Lopez-Rios, Fernando

doi:10.1200/jco.2013.48.9070

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Level of HER2 Gene Amplification Predicts Response and Overall Survival in HER2-Positive Advanced Gastric Cancer Treated With Trastuzumab

Shared by NobleBlocks on Dec 10, 2013 • 12:00 AM UTC

Authors:

Carlos Gomez-Martin

Jose Carlos Plaza

Roberto Pazo-Cid

Abstract

Purpose Previous studies have highlighted the importance of an appropriate human epidermal growth factor receptor 2 (HER2) evaluation for the proper identification of patients eligible for treatment with anti-HER2 targeted therapies. Today, the relationship remains unclear between the level of HER2 ...

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