The Complementary Strand of the Human T-Cell Leukemia Virus Type 1 RNA Genome Encodes a bZIP Transcription Factor That Down-Regulates Viral Transcription

Gaudray, Gilles; Gachon, Frédéric; Basbous, Jihane; Biard‐Piechaczyk, Martine; Devaux, Christian; Mesnard, Jean-Michel

doi:10.1128/jvi.76.24.12813-12822.2002

Public

The Complementary Strand of the Human T-Cell Leukemia Virus Type 1 RNA Genome Encodes a bZIP Transcription Factor That Down-Regulates Viral Transcription

Published in Journal of Virology • Nov 18, 2002

Authors:

Gilles Gaudray

Frédéric Gachon

Jihane Basbous

Abstract

The RNA genome of the human T-cell leukemia virus type 1 (HTLV-1) codes for proteins involved in infectivity, replication, and transformation. We report in this study the characterization of a novel viral protein encoded by the complementary strand of the HTLV-1 RNA genome. This protein, designated ...

Subject

Biology

Transcription (linguistics)

bZIP domain

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