Safety and Benefit of Discontinuing Statin Therapy in the Setting of Advanced, Life-Limiting Illness

S. Kutner, Jean; J. Blatchford, Patrick; H. Taylor, Donald; S. Ritchie, Christine; Bull, Janet; L. Fairclough, Diane; C. Hanson, Laura; W. LeBlanc, Thomas; Samsa, Greg; Wolf, Steven; M. Aziz, Noreen; C. Currow, David; Ferrell, Betty; D. Wagner‐Johnston, Nina; Yousuf Zafar, S.; F. Cleary, James; Dev, Sandesh; S. Goode, Patricia; H. Kamal, Arif; T. Kassner, Cordt; Kvale, Elizabeth; G. McCallum, Janelle; Ogunseitan, Adeboye; Z. Pantilat, Steven; K. Portenoy, Russell; Prince‐Paul, Maryjo; A. Sloan, Jeff; M. Swetz, Keith; F. von Gunten, Charles; P. Abernethy, Amy

doi:10.1001/jamainternmed.2015.0289

Public

Safety and Benefit of Discontinuing Statin Therapy in the Setting of Advanced, Life-Limiting Illness

Published in JAMA Internal Medicine • Mar 23, 2015

Authors:

Jean S. Kutner

Patrick J. Blatchford

Donald H. Taylor

Abstract

IMPORTANCE: For patients with limited prognosis, some medication risks may outweigh the benefits, particularly when benefits take years to accrue; statins are one example. Data are lacking regarding the risks and benefits of discontinuing statin therapy for patients with limited life expectancy. OBJ...

Subject

Medicine

Discontinuation

Randomized controlled trial

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