Changes in Forced Expiratory Volume in 1 Second over Time in COPD

Vestbo, Jørgen; Edwards, Lisa; D. Scanlon, Paul; Yates, Julie; Agustí, Àlvar; Bakke, Per; M.A. Calverley, Peter; R. Celli, Bartolomé; O. Coxson, Harvey; Crim, Courtney; A. Lomas, David; MacNee, William; E. Miller, Bruce; K. Silverman, Edwin; Tal‐Singer, Ruth; Wouters, E.F.M.; I. Rennard, Stephen

doi:10.1056/nejmoa1105482

Public

Changes in Forced Expiratory Volume in 1 Second over Time in COPD

Published in New England Journal of Medicine • Sep 26, 2011

Authors:

Jørgen Vestbo

Lisa Edwards

Paul D. Scanlon

Abstract

BACKGROUND: A key feature of chronic obstructive pulmonary disease (COPD) is an accelerated rate of decline in forced expiratory volume in 1 second (FEV(1)), but data on the variability and determinants of this change in patients who have established disease are scarce. METHODS: We analyzed the chan...

Subject

Medicine

COPD

Bronchodilator

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