Foxl2 Up-Regulates Aromatase Gene Transcription in a Female-Specific Manner by Binding to the Promoter as Well as Interacting with Ad4 Binding Protein/Steroidogenic Factor 1

Wang, De-Shou; Kobayashi, Tohru; Zhou, Lin-Yan; Paul‐Prasanth, Bindhu; Ijiri, Shigeho; Sakai, Fumie; Okubo, Kataaki; Morohashi, Ken-ichirou; Nagahama, Yoshitaka

doi:10.1210/me.2006-0248

Public

Foxl2 Up-Regulates Aromatase Gene Transcription in a Female-Specific Manner by Binding to the Promoter as Well as Interacting with Ad4 Binding Protein/Steroidogenic Factor 1

Published in Molecular Endocrinology • Dec 28, 2006

Authors:

De-Shou Wang

Tohru Kobayashi

Lin-Yan Zhou

Abstract

Increasing evidence suggests the crucial role of estrogen in ovarian differentiation of nonmammalian vertebrates including fish. The present study has investigated the plausible role of Foxl2 in ovarian differentiation through transcriptional regulation of aromatase gene, using monosex fry of tilapi...

Subject

Biology

Aromatase

Transcription factor

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