Sirolimus Use in Liver Transplant Recipients With Hepatocellular Carcinoma

K. Geissler, Edward; A. Schnitzbauer, Andreas; Zülke, C.; Lamby, P.; Proneth, Andrea; Duvoux, Christophe; Burra, Patrizia; Jauch, Karl‐Walter; Rentsch, Markus; M. Ganten, Tom; Schmidt, Jan; Settmacher, Utz; Heise, Michael; Rossi, G.; Cillo, Umberto; M. Kneteman, Norman; Adam, René; van Hoek, Bart; Bachellier, Philippe; Wolf, Philippe; Rostaing, Lionel; O. Bechstein, Wolf; Rizell, Magnus; J. Powell, James; Hidalgo, Ernest; Gugenheim, Jean; Wolters, Heiner; Brockmann, Jens; Roy, André; Mutzbauer, Ingrid; Schlitt, Angela; Beckebaum, Susanne; Graeb, Christian; Nadalin, Silvio; Valente, Umberto; Sánchez Turrión, Víctor; V. Jamieson, Neville; Scholz, Tim; Colledan, M.; Fändrich, Fred; Becker, Thomas; Söderdahl, Gunnar; Chazouillères, Olivier; Mäkisalo, Heikki; Pageaux, Georges‐Philippe; Steininger, Rudolf; Soliman, Thomas; P. de Jong, Koert; Pirenne, Jacques; Margreiter, Raimund; Pratschke, Johann; D. Pinna, Antonio; Hauss, Johann; Schreiber, Stefan; I. Strasser, Simone; Klempnauer, Jürgen; Troisi, Roberto; Bhoori, Sherrie; Lerut, Jan; Bilbao, Itxarone; Klein, Christian; Königsrainer, Alfred; F. Mirza, Darius; Otto, Gerd; Mazzaferro, Vincenzo; Neuhaus, P.; J. Schlitt, Hans

doi:10.1097/tp.0000000000000965

Public

Sirolimus Use in Liver Transplant Recipients With Hepatocellular Carcinoma

Published in Transplantation • Nov 10, 2015

Authors:

Edward K. Geissler

Andreas A. Schnitzbauer

C. Zülke

Abstract

BACKGROUND: We investigated whether sirolimus-based immunosuppression improves outcomes in liver transplantation (LTx) candidates with hepatocellular carcinoma (HCC). METHODS: In a prospective-randomized open-label international trial, 525 LTx recipients with HCC initially receiving mammalian target...

Subject

Sirolimus

Immunosuppression

Medicine

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