Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance

A. Kern, Philip; Ranganathan, Subramanian; Li, Chunling; C. Wood, Linda; Ranganathan, Gouri

doi:10.1152/ajpendo.2001.280.5.e745

Public

Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance

Published in American Journal of Physiology-Endocrinology and Metabolism • May 1, 2001

Authors:

Philip A. Kern

Subramanian Ranganathan

Chunling Li

Abstract

Adipose tissue expresses tumor necrosis factor (TNF) and interleukin (IL)-6, which may cause obesity-related insulin resistance. We measured TNF and IL-6 expression in the adipose tissue of 50 lean and obese subjects without diabetes. Insulin sensitivity (S(I)) was determined by an intravenous gluco...

Subject

Adipose tissue

Internal medicine

Endocrinology

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