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Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance.

Published in American journal of physiology. Endocrinology and metabolism • May 1, 2001
Authors:
P A Kern
,
S Ranganathan
,
C Li

Abstract

Adipose tissue expresses tumor necrosis factor (TNF) and interleukin (IL)-6, which may cause obesity-related insulin resistance. We measured TNF and IL-6 expression in the adipose tissue of 50 lean and obese subjects without diabetes. Insulin sensitivity (S(I)) was determined by an intravenous gluco...

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