<sup>68</sup>Ga- and <sup>177</sup>Lu-Labeled PSMA I&amp;T: Optimization of a PSMA-Targeted Theranostic Concept and First Proof-of-Concept Human Studies

Weineisen, Martina; Schottelius, Margret; Šimeček, Jakub; P. Baum, Richard; Yıldız, Akın; Beykan, Seval; Kulkarni, Harshad; Laßmann, Michael; Klette, Ingo; Eiber, Matthias; Schwaiger, Markus; Wester, Hans‐Jürgen

doi:10.2967/jnumed.115.158550

Public

68Ga- and 177Lu-Labeled PSMA I&T: Optimization of a PSMA-Targeted Theranostic Concept and First Proof-of-Concept Human Studies

Published in Journal of Nuclear Medicine • Jun 18, 2015

Authors:

Martina Weineisen

Margret Schottelius

Jakub Šimeček

Abstract

UNLABELLED: On the basis of the high and consistent expression of prostate-specific membrane antigen (PSMA) in metastatic prostate cancer (PC), the goal of this study was the development, preclinical evaluation, and first proof-of-concept investigation of a PSMA inhibitor for imaging and therapy (PS...

Subject

LNCaP

Biodistribution

Glutamate carboxypeptidase II

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