High PD-L1 Expression Correlates with Metastasis and Poor Prognosis in Oral Squamous Cell Carcinoma

Lin, Yueh-Min; Sung, Wen‐Wei; Hsieh, Ming-Ju; Tsai, Shih-Chen; Lai, Hung-Wen; Yang, Shu-Mei; Shen, Ko-Hong; Chen, Mu-Kuan; Lee, Huei; Yeh, Kun-Tu; Chen, Chih‐Jung

doi:10.1371/journal.pone.0142656

Public

High PD-L1 Expression Correlates with Metastasis and Poor Prognosis in Oral Squamous Cell Carcinoma

Published in PLoS ONE • Nov 12, 2015

Authors:

Yueh-Min Lin

Wen‐Wei Sung

Ming-Ju Hsieh

Abstract

PD-L1 has been widely demonstrated to contribute to failed antitumor immunity. Blockade of PD-L1 with monoclonal antibody could modulate the tumor immune environment to augment immunotherapy. PD-L1 expression is also detected in several types of cancer and is associated with poor prognosis. However,...

Subject

Hazard ratio

Medicine

Immunohistochemistry

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